NAT14 and MARCO

		NAT14	MARCO
Description		N-acetyltransferase 14 (putative)	macrophage receptor with collagenous structure
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Integral Component Of Membrane	Collagen Trimer Intracellular Anatomical Structure Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Membrane
	Molecular Function	DNA Binding N-acetyltransferase Activity	Amyloid-beta Binding G Protein-coupled Receptor Binding Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Cargo Receptor Activity Pattern Recognition Receptor Activity
	Biological Process	DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated	Positive Regulation Of Protein Phosphorylation Endocytosis Receptor-mediated Endocytosis Phagocytosis, Engulfment Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Apoptotic Cell Clearance Innate Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Amyloid-beta Clearance
Pathways			Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs			Titanium dioxide Silicon dioxide
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Lung function (FVC) ( 30061609) Medication use (adrenergics, inhalants) ( 31015401) Triglyceride levels ( 32203549)
Interacting Genes		14 interacting genes: ADRB2 CCR4 F2RL1 GALP HTR2B ISOC2 JUN MARCO MLC1 MOV10L1 RABAC1 YAE1 ZNF581 ZNF628	4 interacting genes: NAT14 SAP130 SCGB3A1 SCGB3A2
Entrez ID		57106	8685
HPRD ID		10036	05337
Ensembl ID		ENSG00000090971	ENSG00000019169
Uniprot IDs		Q8WUY8	Q4ZG40 Q9UEW3
PDB IDs
Enriched GO Terms of Interacting Partners?
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