CIAPIN1 and CACNB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CIAPIN1	CACNB3
Description		cytokine induced apoptosis inhibitor 1	calcium voltage-gated channel auxiliary subunit beta 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Intermembrane Space	Cytosol Voltage-gated Calcium Channel Complex Membrane Apical Plasma Membrane Synapse L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Protein Binding Methyltransferase Activity Electron Transfer Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding High Voltage-gated Calcium Channel Activity Protein Kinase Binding
	Biological Process	Apoptotic Process Iron-sulfur Cluster Assembly Electron Transport Chain Hemopoiesis Negative Regulation Of Apoptotic Process	Calcium Ion Transport Chemical Synaptic Transmission Neuromuscular Junction Development T Cell Receptor Signaling Pathway Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Cellular Response To Oxygen-glucose Deprivation Regulation Of Membrane Repolarization During Action Potential Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Membrane Hyperpolarization Negative Regulation Of Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Cytosolic iron-sulfur cluster assembly	Presynaptic depolarization and calcium channel opening Adrenaline,noradrenaline inhibits insulin secretion NCAM1 interactions Regulation of insulin secretion Regulation of insulin secretion
Drugs			Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Nimodipine Spironolactone Magnesium sulfate Levomenthol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases
GWAS
Interacting Genes		6 interacting genes: CACNB3 CHCHD4 GLRX3 MEOX2 NDOR1 OSGEP	13 interacting genes: C20orf85 CACNA1B CACNA1C CDK2 CEP76 CIAPIN1 CTBP2 FASLG GEM MEOX1 MTUS2 SKIV2L SYT1
Entrez ID		57019	784
HPRD ID		12338	11879
Ensembl ID		ENSG00000005194	ENSG00000167535
Uniprot IDs		H3BT65 Q6FI81	P54284
PDB IDs		2LD4 2YUI 4M7R
Enriched GO Terms of Interacting Partners?
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