CCNL1 and ZRSR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCNL1	ZRSR2
Description		cyclin L1	zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Protein Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II RNA Processing	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing
Pathways			mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Adiponectin levels in pregnancy ( 28317342) Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Anthropometric traits in newborns ( 23575227) Birth weight ( 23202124 31453325 31043758 27680694 20372150) Birth weight variance ( 31453325) Body fat percentage variance ( 31453325) Body mass index ( 26426971) circulating leptin levels ( 32917775 26833098) circulating leptin levels adjusted for BMI ( 32917775 26833098) Coronary artery disease ( 33020668) Diabetic retinopathy ( 21441570) Eating disorders ( 22911880) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Menarche (age at onset) ( 25231870) Offspring birth weight ( 31043758) PR interval ( 30046033 32439900) Smoking cessation in chronic obstructive pulmonary disease ( 21685187)
Interacting Genes		22 interacting genes: APP APPBP2 C1orf35 CASP8 CDK11A DVL3 FAM133A JMJD6 KRTAP12-2 NKAPD1 PRDM6 PRPF40A RAD51D RNPS1 RSRP1 SAP30BP SORBS3 SREK1IP1 SRSF2 TFIP11 ZRANB1 ZRSR2	20 interacting genes: APP CCNL1 CLK2 DVL3 KHDC4 LUC7L2 REP15 SDCBP2 SLC2A1 SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2 ZRSR2P1
Entrez ID		57018	8233
HPRD ID		10814	02068
Ensembl ID		ENSG00000163660	ENSG00000169249
Uniprot IDs		Q9UK58	Q15696
PDB IDs
Enriched GO Terms of Interacting Partners?
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