CTNNBIP1 and GINS4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CTNNBIP1	GINS4
Description		catenin beta interacting protein 1	GINS complex subunit 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex	GINS Complex Nucleoplasm Cytoplasm CMG Complex
	Molecular Function	Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding	Protein Binding
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein Binding Negative Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation	Double-strand Break Repair Via Break-induced Replication Inner Cell Mass Cell Proliferation DNA-dependent DNA Replication
Pathways		Deactivation of the beta-catenin transactivating complex	Unwinding of DNA Unwinding of DNA
Drugs
Diseases
GWAS		Platelet distribution width ( 32888494) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		19 interacting genes: BEND5 CTNNA2 CTNNB1 EMD GINS4 INCA1 JUP KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP5-9 MSS51 NBPF19 NOTCH2NLA P4HA3 REL SPATA24 TCF7L2 USHBP1	18 interacting genes: - BIN3 CDC45 CTNNBIP1 DMAP1 GINS1 GINS2 GINS3 IDO2 KIF16B LHX8 MCM2 PBX4 POLA1 POLD1 POLE PPP1R13B SIK1
Entrez ID		56998	84296
HPRD ID		09677	11583
Ensembl ID		ENSG00000178585	ENSG00000147536
Uniprot IDs		A0A024R4D7 Q9NSA3	Q9BRT9
PDB IDs		1LUJ 1M1E 1T08	2E9X 2EHO 2Q9Q 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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