ARNTL2 and CTTNBP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARNTL2	CTTNBP2
Description		aryl hydrocarbon receptor nuclear translocator like 2	cortactin binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Aryl Hydrocarbon Receptor Complex	Cell Cortex Synaptic Vesicle Dendritic Spine Postsynaptic Actin Cytoskeleton Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Dimerization Activity E-box Binding	Protein Binding SH3 Domain Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Entrainment Of Circadian Clock Positive Regulation Of Circadian Rhythm Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Brain Development Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS		Body fat percentage ( 31752434) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Idiopathic osteonecrosis of the femoral head ( 28000841) Intraocular pressure ( 29617998 29785010 31959993 30054594) Myocardial infarction ( 33532862) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (current vs never) ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Sociability score ( 34054130) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 30108155) Type 2 diabetes ( 30054458 30297969) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Worry too long after an embarrassing experience ( 34054130)
Interacting Genes		6 interacting genes: CLOCK CTTNBP2 EPAS1 MEOX2 NPAS2 RORC	11 interacting genes: APPL1 ARNTL2 CTTN FAM86C1P HSF2BP IMMP2L INCA1 KRT14 MAGEA11 MEI4 PKNOX2
Entrez ID		56938	83992
HPRD ID		16507	09890
Ensembl ID		ENSG00000029153	ENSG00000077063
Uniprot IDs		Q8WYA1	Q20BG9 Q8WZ74
PDB IDs		2KDK
Enriched GO Terms of Interacting Partners?
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