KCNQ5 and KCNQ3

Number of citations of the paper that reports this interaction (PubMedID 12890507)
23

Data Source:
HPRD (in vivo)

		KCNQ5	KCNQ3
Description		potassium voltage-gated channel subfamily Q member 5	potassium voltage-gated channel subfamily Q member 3
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Clathrin Coat	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Node Of Ranvier Axon Initial Segment Synapse
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding
	Biological Process	Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport	Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Membrane Hyperpolarization Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels Interaction between L1 and Ankyrins
Drugs		Enflurane Gabapentin Promethazine Miconazole Ezogabine ICA-105665	Enflurane Amitriptyline Meclofenamic acid Gabapentin Promethazine Miconazole Ezogabine ICA-105665
Diseases
GWAS		Carotid plaque burden ( 28282560) Cataracts ( 34127677) Frontal pole volume ( 31530798) High myopia ( 31816047) HIV-1 viral setpoint ( 26039976) Lung function (FEV1/FVC) ( 28166213 30804560) Lung function (FVC) ( 30804560) Myopia ( 27182965) Optic disc size ( 31809533) Peak expiratory flow ( 30804560) Periodontitis ( 25672891) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Pulse pressure ( 30224653) Refractive error ( 23396134 32231278) Rosacea symptom severity ( 29771307) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Total body bone mineral density ( 30172743) Upper eyelid sagging severity ( 24869959) Western dietary pattern ( 28644415)	Coronary artery calcification ( 23870195) Height ( 28552196) LDL peak particle diameter (total fat intake interaction) ( 26112879) QT interval ( 29213071) Type 2 diabetes ( 31324766)
Interacting Genes		8 interacting genes: CALM1 CALM2 CALM3 DISC1 KCNQ3 MTDH POU3F2 SRC	9 interacting genes: CALM1 CALM2 CALM3 CHAT KCNQ2 KCNQ4 KCNQ5 THBS1 TNFRSF10B
Entrez ID		56479	3786
HPRD ID		16241	09077
Ensembl ID		ENSG00000185760	ENSG00000184156
Uniprot IDs		Q9NR82	O43525
PDB IDs		6B8Q	5J03
Enriched GO Terms of Interacting Partners?
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