PRSS2 and DMBT1

		PRSS2	DMBT1
Description		serine protease 2	deleted in malignant brain tumors 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Azurophil Granule Lumen	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of Membrane Phagocytic Vesicle Membrane Extracellular Matrix Zymogen Granule Membrane Extracellular Exosome
	Molecular Function	Metalloendopeptidase Activity Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Serine-type Peptidase Activity	Scavenger Receptor Activity Protein Binding Zymogen Binding Pattern Recognition Receptor Activity Calcium-dependent Protein Binding Extracellular Matrix Binding
	Biological Process	Proteolysis Digestion Antimicrobial Humoral Response Extracellular Matrix Disassembly Positive Regulation Of Cell Growth Collagen Catabolic Process Positive Regulation Of Cell Adhesion	Endocytosis Defense Response Protein Transport Epithelial Cell Differentiation Detection Of Bacterial Lipoprotein Induction Of Bacterial Agglutination Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus
Pathways		Collagen degradation Alpha-defensins Activation of Matrix Metalloproteinases Neutrophil degranulation Antimicrobial peptides	Surfactant metabolism
Drugs		Monoisopropylphosphorylserine O-Benzylsulfonyl-Serine Benzylamine Benzamidine Phosphorylisopropane Phenethylamine 3-Phenylpropylamine
Diseases
GWAS		Blood protein levels ( 29875488) Pancreatitis ( 23143602)	Iris heterochromicity ( 30895295)
Interacting Genes		9 interacting genes: APP BPI CSN1S1 DMBT1 GLP1R MKKS MMP9 SERPINA1 SLPI	7 interacting genes: GNB3 MEAF6 MRPS6 PRSS2 SELENBP1 SFTPA1 SFTPD
Entrez ID		5645	1755
HPRD ID		03335	03575
Ensembl ID		ENSG00000275896	ENSG00000187908
Uniprot IDs		A6XMV9 P07478 Q5NV56 Q6PK75	A0A590UJ76 Q9UGM3
PDB IDs			6SA4 6SA5 6SAN
Enriched GO Terms of Interacting Partners?
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