PRODH and TBX1

		PRODH	TBX1
Description		proline dehydrogenase 1	T-box transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle	Chromatin Nucleus
	Molecular Function	Proline Dehydrogenase Activity FAD Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Proline Metabolic Process Proline Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Proline Catabolic Process To Glutamate Positive Regulation Of Cell Death 4-hydroxyproline Catabolic Process	Angiogenesis Blood Vessel Development Cell Fate Specification Neural Crest Cell Migration Positive Regulation Of Protein Phosphorylation Lymph Vessel Development Positive Regulation Of Mesenchymal Cell Proliferation Heart Morphogenesis Outflow Tract Septum Morphogenesis Outflow Tract Morphogenesis Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Pattern Specification Process Mesoderm Development Heart Development Muscle Organ Development Sensory Perception Of Sound Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Anterior/posterior Pattern Specification Vagus Nerve Morphogenesis Epithelial Cell Differentiation Thyroid Gland Development Social Behavior Aorta Morphogenesis Ear Morphogenesis Inner Ear Morphogenesis Outer Ear Morphogenesis Middle Ear Morphogenesis Odontogenesis Of Dentin-containing Tooth Muscle Cell Fate Commitment Positive Regulation Of MAPK Cascade Tongue Morphogenesis Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Blood Vessel Morphogenesis Thymus Development Muscle Organ Morphogenesis Embryonic Cranial Skeleton Morphogenesis Embryonic Viscerocranium Morphogenesis Semicircular Canal Morphogenesis Artery Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Parathyroid Gland Development Soft Palate Development Pharyngeal System Development Face Morphogenesis Muscle Tissue Morphogenesis Coronary Artery Morphogenesis Enamel Mineralization Cellular Response To Retinoic Acid Cochlea Morphogenesis Mesenchymal Cell Apoptotic Process Regulation Of Animal Organ Morphogenesis Positive Regulation Of Tongue Muscle Cell Differentiation Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways		Proline catabolism
Drugs		Proline
Diseases
GWAS		Amino acid levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Metabolic traits ( 21886157) Metabolite levels ( 31628463) Neutrophil count ( 32888494) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free proline levels ( 30659259) Platelet count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748 25569235) White blood cell count ( 32888494)	Acute kidney injury in critical illness ( 27576016) Adolescent idiopathic scoliosis ( 31417091) Childhood ear infection ( 27182965 28928442) DNA methylation (parent-of-origin) ( 23725790) Interleukin-10 levels ( 22205395) Myringotomy ( 28928442) Prostate cancer ( 25217961) Rheumatoid arthritis ( 30891314) Schizophrenia ( 26198764) Tonsillectomy ( 27182965 28928442)
Interacting Genes		7 interacting genes: GGT3P GSC2 ITM2C RANBP1 SEPTIN5 SKIV2L TBX1	2 interacting genes: MORC3 PRODH
Entrez ID		5625	6899
HPRD ID		08433	09069
Ensembl ID		ENSG00000100033	ENSG00000184058
Uniprot IDs		O43272	D9ZGG0 O43435 Q152R5
PDB IDs			4A04
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?