PRKCSH and GANAB

Number of citations of the paper that reports this interaction (PubMedID 22863883)
127

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		PRKCSH	GANAB
Description		protein kinase C substrate 80K-H	glucosidase II alpha subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Glucosidase II Complex Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Glucosidase II Complex Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Kinase C Binding Calcium Ion Binding Protein Binding Transmembrane Transporter Binding Phosphoprotein Binding	RNA Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding Carbohydrate Binding Glucan 1,3-alpha-glucosidase Activity Alpha-glucosidase Activity
	Biological Process	Liver Development N-glycan Processing Intracellular Signal Transduction	Carbohydrate Metabolic Process N-glycan Processing
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Advanced glycosylation endproduct receptor signaling Post-translational protein phosphorylation Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein	N-glycan trimming in the ER and Calnexin/Calreticulin cycle Calnexin/calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs			Miglitol
Diseases
GWAS		Presence of antiphospholipid antibodies ( 27098658) Serum metabolite levels (CMS) ( 31636271)	Body shape index ( 34021172) Hip index ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		12 interacting genes: ARL4D CANX ESR1 FXR1 GANAB GBA3 GET4 PTPRC RGS2 RPS6 SMARCA4 VDR	9 interacting genes: CCNH CREB3L4 CSNK2A1 LINC01554 MAPK8 PRKCSH PRRC2A PTPRC RAP1A
Entrez ID		5589	23193
HPRD ID		03518	03516
Ensembl ID		ENSG00000130175	ENSG00000089597
Uniprot IDs		B4DJQ5 K7ELL7 P14314	B4DIW2 B4DSM6 B4DZ53 E9PKU7 F5H6X6 Q14697 V9HWJ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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