PRKCH and PPP1R14A

Number of citations of the paper that reports this interaction (PubMedID 15003508)
13

Data Source:
BioGRID (pull down)

		PRKCH	PPP1R14A
Description		protein kinase C eta	protein phosphatase 1 regulatory inhibitor subunit 14A
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Extracellular Exosome	Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Enzyme Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Peptidyl-serine Phosphorylation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly	Regulation Of Phosphorylation Negative Regulation Of Catalytic Activity
Pathways		Effects of PIP2 hydrolysis G alpha (z) signalling events	RHO GTPases activate PKNs
Drugs
Diseases
GWAS		Asthma ( 32296059) Height ( 28552196) Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 30423114 22446963 24390342) Word reading ( 23738518) Yeast infection ( 28928442)	Diverticular disease ( 30177863)
Interacting Genes		17 interacting genes: BANP BMP4 C14orf39 CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SIX6 SRC ZBTB8OS ZFP36L1 ZFYVE1	16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		5583	94274
HPRD ID		05669	16291
Ensembl ID		ENSG00000027075	ENSG00000167641
Uniprot IDs		P24723	Q96A00
PDB IDs		2FK9 3TXO
Enriched GO Terms of Interacting Partners?
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