ENAH and ROBO4

Number of citations of the paper that reports this interaction (PubMedID 12941633)
120

Data Source:
HPRD (in vitro)

		ENAH	ROBO4
Description		ENAH actin regulator	roundabout guidance receptor 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium Cell Junction Filopodium Synapse	Plasma Membrane Integral Component Of Membrane Axon Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding WW Domain Binding	Protein Binding Signaling Receptor Activity Cell-cell Adhesion Mediator Activity
	Biological Process	Axon Guidance Actin Polymerization Or Depolymerization Actin Polymerization-dependent Cell Motility	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Regulation Of Cell Migration Establishment Of Endothelial Barrier Dendrite Self-avoidance
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors
Drugs
Diseases
GWAS		Delirium ( 29631748) Depression in smokers ( 30219690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Neuroticism ( 27067015) Obesity-related traits ( 23251661)	Breast cancer (survival) ( 25890600) Venous thromboembolism ( 32232851)
Interacting Genes		28 interacting genes: ABI1 ABI2 ABI3 ABL1 APBB1 BAIAP2 DNAH14 DNMBP EVL FAT1 FYB1 GPHN HMGB1 KLHDC3 MAPK1 PFN1 PRPF40A RAC1 RAD51 ROBO4 SPTA1 TERF2IP TES VASP WAS XIRP1 YAP1 ZYX	5 interacting genes: CEP19 ENAH PPARG RXRA THRB
Entrez ID		55740	54538
HPRD ID		12360	09604
Ensembl ID		ENSG00000154380	ENSG00000154133
Uniprot IDs		A0A4D6J698 Q8N8S7	B4DYV8 Q8WZ75
PDB IDs		2HO2 2IYB 2XQN 4MY6 5N91 5N9C 5N9P 5NAJ 5NBF 5NBX 5NC2 5NC7 5NCF 5NCG 5NCP 5ND0 5NDU 5NEG 6RCF 6RCJ 6RD2 6XVT 6XXR 7A5M 7AKI
Enriched GO Terms of Interacting Partners?
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