CCDC88A and EXOC1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
193

Data Source:
BioGRID (two hybrid)

		CCDC88A	EXOC1
Description		coiled-coil domain containing 88A	exocyst complex component 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Centriole Cytosol Plasma Membrane Membrane Lamellipodium COPI-coated Golgi To ER Transport Vesicle Cytoplasmic Vesicle Ciliary Basal Body	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane
	Molecular Function	G-protein Alpha-subunit Binding Actin Binding Protein Kinase C Binding Guanyl-nucleotide Exchange Factor Activity GDP-dissociation Inhibitor Activity Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Microtubule Binding G-protein Gamma-subunit Binding Phosphatidylinositol Binding SH2 Domain Binding Protein Homodimerization Activity Vascular Endothelial Growth Factor Receptor 2 Binding Protein Kinase B Binding Dynein Light Intermediate Chain Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Regulation Of Protein Phosphorylation DNA Replication Regulation Of DNA Replication Small GTPase Mediated Signal Transduction Nervous System Development Regulation Of Neuron Projection Development Cell Migration Lamellipodium Assembly Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization TOR Signaling Activation Of Protein Kinase Activity Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization Regulation Of Cell Population Proliferation Positive Regulation Of Cilium Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly Membrane Organization Maintenance Of Protein Location In Plasma Membrane Positive Regulation Of Protein Localization To Cilium	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus
Pathways		RND3 GTPase cycle RND1 GTPase cycle	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Height ( 21998595) Periventricular white matter hyperintensities ( 32517579) Refractive error ( 32231278)	Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: AKT1 BRAF DISC1 EGFR EXOC1 GNAI3 INSR KDR NDEL1 PRKACA PTPN6	29 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIO
Entrez ID		55704	55763
HPRD ID		11131	07615
Ensembl ID		ENSG00000115355	ENSG00000090989
Uniprot IDs		A0A2U3TZV9 O14997 Q3V6T2	A0A024RDA1 A1LT29 Q9NV70
PDB IDs		6MHF
Enriched GO Terms of Interacting Partners?
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