PACS1 and CLCN7

Number of citations of the paper that reports this interaction (PubMedID 15692563)
86

Data Source:
HPRD (in vitro)

		PACS1	CLCN7
Description		phosphofurin acidic cluster sorting protein 1	chloride voltage-gated channel 7
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol COPI-coated Vesicle	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Transmembrane Transporter Binding	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity
	Biological Process	Protein Localization To Golgi Apparatus Protein Localization To Plasma Membrane	Response To PH Chloride Transmembrane Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression	Stimuli-sensing channels
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 21926972 33263727 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Electroencephalogram traits ( 25387704) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Obesity (early onset extreme) ( 23563609) Serum uric acid levels ( 32514006) Waist circumference adjusted for body mass index ( 34021172)	Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)
Interacting Genes		20 interacting genes: AOPEP CABP4 CARNS1 CLCN7 CSNK2A1 FURIN GDI1 GGA3 IGF2R JUN KLC2 LAMA4 MCAM OTUB1 PKD2 PPP2CA PPP2CB SLC24A1 USP9Y VAMP4	16 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B
Entrez ID		55690	1186
HPRD ID		06320	04103
Ensembl ID		ENSG00000175115	ENSG00000103249
Uniprot IDs		A0A024R5H6 Q6VY07	P51798
PDB IDs			7BXU 7CQ5 7CQ6 7CQ7 7JM7
Enriched GO Terms of Interacting Partners?
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