ASAP3 and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ASAP3	TFCP2
Description		ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	transcription factor CP2
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Migration Positive Regulation Of GTPase Activity Regulation Of Stress Fiber Assembly	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) LDL cholesterol levels ( 32203549) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)
Interacting Genes		9 interacting genes: ARF6 CRK MTNR1A PDZD3 REL TCF4 TEPSIN TFCP2 UBE3A	74 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I UBP1 YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		55616	7024
HPRD ID		11662	01790
Ensembl ID		ENSG00000088280	ENSG00000135457
Uniprot IDs		A0A024RAB1 B4DRP2 Q8TDY4	A0A024R120 Q12800
PDB IDs		2B0O 3LVQ 3LVR
Enriched GO Terms of Interacting Partners?
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