OTUB1 and H2AX

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

OTUB1

H2AX

Description OTU deubiquitinase, ubiquitin aldehyde binding 1 H2A.X variant histone
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 58 interacting genes: ACVR1 ACVR1B ANXA1 ANXA7 AURKA BIRC2 BMPR1A BMPR1B CD274 CDKN1A CPEB2 CSNK2A1 ECT2 ESR1 FOXM1 H2AX IL1RL2 KDM1A MAPT NEDD8 PACS1 PJA1 RFFL RHOA RNF126 RNF128 SLC7A11 SMAD2 SMAD3 SMAD4 SMAD9 SNAI1 TGFBR1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TSC22D1 TTR UBA6 UBC UBD UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2N UBE2S UBE2V2 UBE2Z UBE4B USP15 USP21 USP28 45 interacting genes: A2M ACTB ALG9 ATM ATR BARD1 BAZ1B BMI1 BRCA1 BRCA2 BRD1 CALM1 COPG1 DDX21 DHX9 EYA1 HUWE1 KAT5 MASP1 MDC1 MRE11 NBN NCL NGFR OTUB1 PAXIP1 PBK PPP1CA PRKDC PTEN PTPA QARS1 RNF8 RPS6KA3 SMARCA4 SUPT5H TAF1C TAF5L TERF2 TIAM2 TOPORS TP53BP1 TRAF6 TSSK6 WRN
Entrez ID 55611 3014
HPRD ID 08493 03465
Ensembl ID ENSG00000167770 ENSG00000188486
Uniprot IDs B3KUV5 Q96FW1 P16104
PDB IDs 2ZFY 3VON 4DDG 4DDI 4DHZ 4I6L 4LDT 1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z 6K1I 6K1J 6K1K
Enriched GO Terms of Interacting Partners?
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