BBS7 and ANXA5

		BBS7	ANXA5
Description		Bardet-Biedl syndrome 7	annexin A5
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleus Centrosome Cytosol Axoneme Membrane BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane	Extracellular Region Cytoplasm Cytosol Focal Adhesion Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding
	Biological Process	Eye Development Heart Looping Regulation Of Transcription By RNA Polymerase II Smoothened Signaling Pathway Determination Of Left/right Symmetry Brain Development Visual Perception Protein Localization Protein Transport Melanosome Transport Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fat Cell Differentiation Intracellular Transport Digestive Tract Morphogenesis Pigment Granule Aggregation In Cell Center Limb Development Cilium Assembly Primary Palate Development Non-motile Cilium Assembly	Signal Transduction Blood Coagulation Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Coagulation
Pathways		BBSome-mediated cargo-targeting to cilium	Platelet degranulation
Drugs			Fluocinolone acetonide L-Alpha-Glycerophosphorylserine L-thioproline K201 free base sn-glycero-3-phosphoethanolamine 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid N,O6-Disulfo-Glucosamine 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Copper
Diseases
GWAS		Asthma ( 31959851) Hip circumference adjusted for BMI ( 34021172) Psoriasis ( 31376382)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Body shape index ( 34021172) Resting-state electroencephalogram vigilance ( 29703947) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: ANXA5 CNGA1 FHOD1 JUN KRT18 MAD2L1 MSH6 NDNF PAX2 PDE8B QRFPR TRPC3	21 interacting genes: ACTG1 APP BBS7 COL10A1 COL2A1 EED EIF4G1 FDFT1 GSC2 IFNGR2 ITGB5 KDR LAMC3 LINC01554 MAD1L1 PPP2R1B SUPT4H1 TERF1 TERF2 TERF2IP TINF2
Entrez ID		55212	308
HPRD ID		07399	00568
Ensembl ID		ENSG00000138686	ENSG00000164111
Uniprot IDs		Q8IWZ6	P08758 V9HWE0
PDB IDs			1ANW 1ANX 1AVH 1AVR 1HAK 1HVD 1HVE 1HVF 1HVG 1SAV 2XO2 2XO3 6K22 6K25
Enriched GO Terms of Interacting Partners?
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