DPPA4 and MAGOH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DPPA4	MAGOH
Description		developmental pluripotency associated 4	mago homolog, exon junction complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	Chromatin Binding Protein Binding	RNA Binding Protein Binding
	Biological Process	System Development Lung-associated Mesenchyme Development	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Regulation Of Translation RNA Splicing MRNA Transport
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		35 interacting genes: BTBD2 CIR1 CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM	20 interacting genes: ALYREF B4GALT2 CEP70 CORO1A DPH2 DPPA4 EIF4A3 FXR1 GOLGA2 IPO13 MAP1B NXF1 PPP1R16B RBM8A TADA2A UPF3B XIST YWHAQ ZKSCAN8 ZRANB1
Entrez ID		55211	4116
HPRD ID		16836	04005
Ensembl ID		ENSG00000121570	ENSG00000162385
Uniprot IDs		Q7L190	P61326
PDB IDs			1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 7A5P
Enriched GO Terms of Interacting Partners?
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