ARL8B and VPS41

Number of citations of the paper that reports this interaction (PubMedID 25908847)
45

Data Source:
BioGRID (pull down)

		ARL8B	VPS41
Description		ADP ribosylation factor like GTPase 8B	VPS41 subunit of HOPS complex
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Vacuolar Membrane Cytosol Membrane Midbody Late Endosome Membrane Synapse Spindle Midzone Extracellular Exosome Cytolytic Granule Membrane Axon Cytoplasm	Lysosome Lysosomal Membrane Early Endosome Late Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Microtubule Cytoskeleton Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane Lysosomal HOPS Complex
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Alpha-tubulin Binding Beta-tubulin Binding	Protein Binding Microtubule Binding Identical Protein Binding Protein Self-association Metal Ion Binding
	Biological Process	Plasma Membrane Repair Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Following Phagocytosis Cell Cycle Chromosome Segregation Anterograde Axonal Transport Protein Transport Endosomal Transport Lysosome Localization Natural Killer Cell Mediated Cytotoxicity Viral Exocytosis Cell Division Autophagosome-lysosome Fusion Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Phagosome-lysosome Fusion Late Endosome To Lysosome Transport Calcium Ion Regulated Lysosome Exocytosis	Protein Targeting To Vacuole Endosome To Lysosome Transport Cellular Response To Starvation Macroautophagy Endosomal Vesicle Fusion Regulated Exocytosis Late Endosome To Lysosome Transport
Pathways
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301)	Breast cancer and/or colorectal cancer ( 29698419) Cognitive performance ( 19734545)
Interacting Genes		11 interacting genes: AMH APP ATP5MF BTN3A3 CIDEB DLEU1 SLC30A8 TGFBR1 TMEM14B TUBB VPS41	14 interacting genes: AKTIP AP3D1 APP ARID1A ARL8B GSDME HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP UBE2U ZNF512B
Entrez ID		55207	27072
HPRD ID		12483	10402
Ensembl ID		ENSG00000134108	ENSG00000006715
Uniprot IDs		Q9NVJ2	P49754
PDB IDs		2AL7
Enriched GO Terms of Interacting Partners?
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