PPP2CA and ADCY8

  • Number of citations of the paper that reports this interaction (PubMedID 16258073)
  • 19
  • Data Source:
  • HPRD (two hybrid, in vitro)

PPP2CA

ADCY8

Description protein phosphatase 2 catalytic subunit alpha adenylate cyclase 8
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054)
  • Cerebral amyloid deposition (PET imaging) ( 30361487)
  • Chronotype ( 26955885)
  • Diisocyanate-induced asthma ( 25918132)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • Lung cancer in ever smokers ( 28604730)
  • Mild to moderate chronic kidney disease ( 31178898)
  • Morning vs. evening chronotype ( 26955885)
  • Post-traumatic stress disorder ( 24677629)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
  • Visceral adipose tissue ( 26480920)
Interacting Genes 97 interacting genes: ADCY8 AKAP6 AKT1 AKT3 AMOTL2 APC AXIN1 BCL2 BEST1 BMPR1B BRAF C3orf36 CAD CAMK1 CARD11 CAV1 CCNG1 CCNG2 CDC42BPB CDK2 CDK6 CDKN2C CEBPA CHEK2 CLPP CSNK2B CXCR2 DELEC1 DVL3 EEF2 EIF4EBP1 ETF1 FCAR GABRB3 GAD1 GOLGA2 HTT IGBP1 IL3 ISYNA1 JAK2 KISS1R L3MBTL3 MAPK1 MAPK3 MAPT MID1 MRPS26 MYC MYH9 NME2 NOSIP NXN PACS1 PAK1 PIM1 PPP1CA PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R5B PPP2R5C PPP2R5E PRKAA1 PRKCD PTEN PTN PXN PYGM RACGAP1 RBL2 RELA RHO RHOB RORC RPS6KB1 RRAS SET SGK1 SGO1 SGO2 STAT5A STAT5B STRN TIAM1 TLX1 TP53 TRIM28 TRIM35 TRIP13 TSC2 UBAP2 VAC14 VDR XRN1 YPEL3 3 interacting genes: CALM1 CALM2 PPP2CA
Entrez ID 5515 114
HPRD ID 08912 00051
Ensembl ID ENSG00000113575 ENSG00000155897
Uniprot IDs B3KUN1 P67775 A0A0K0K1K3 P40145 Q4F7X0
PDB IDs 2IAE 2IE3 2IE4 2NPP 2NYL 2NYM 3C5W 3DW8 3FGA 3K7V 3K7W 3P71 4I5L 4I5N 4IYP 4LAC 5W0W 6NTS 7CUN
Enriched GO Terms of Interacting Partners?
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