LARP1B and POLR2J

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		LARP1B	POLR2J
Description		La ribonucleoprotein 1B	RNA polymerase II subunit J
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm RNA Polymerase II, Core Complex
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Activity DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding LRR Domain Binding Protein Dimerization Activity
	Biological Process		Transcription By RNA Polymerase II
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis MicroRNA (miRNA) biogenesis Transcriptional regulation by small RNAs PIWI-interacting RNA (piRNA) biogenesis Activation of anterior HOX genes in hindbrain development during early embryogenesis RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Serum alkaline phosphatase levels ( 33547301)	Chronotype ( 30696823)
Interacting Genes		11 interacting genes: APP KIF2A MEOX2 MRPL28 PIBF1 POLR2J RABIF RBBP8NL TBC1D25 TRIM69 UBC	15 interacting genes: AATF BAG6 CCDC153 CD14 LARP1B MYOG NTAQ1 OIP5 POLR2C SATB1 SDCBP SNAPC5 TENM1 TRAF4 VPS37C
Entrez ID		55132	5439
HPRD ID		10963	16038
Ensembl ID		ENSG00000138709	ENSG00000005075
Uniprot IDs		A0A3B3ISF0 A0A3B3IT29 G3V0E9 Q659C4	P52435
PDB IDs			5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6DRD 6O9L
Enriched GO Terms of Interacting Partners?
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