FANCL and RIMBP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FANCL	RIMBP3
Description		FA complementation group L	RIMS binding protein 3
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Nuclear Body Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex	Manchette Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Benzodiazepine Receptor Binding
	Biological Process	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Interstrand Cross-link Repair Regulation Of Cell Population Proliferation	Neuromuscular Synaptic Transmission Spermatid Development Fertilization
Pathways		Fanconi Anemia Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 31453325 20935630) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Childhood absence epilepsy ( 30531953) Chronotype ( 30696823) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Daytime nap ( 33568662) Epilepsy ( 25087078 30531953) Feeling miserable ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Generalized epilepsy ( 30531953) HDL cholesterol levels ( 32203549) Hirschsprung disease ( 27702942) Initial pursuit acceleration ( 29064472) Irritable mood ( 29500382) Obesity ( 23563607) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Schizophrenia ( 25056061 29483656) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077) Triglyceride levels ( 32203549) Type 2 diabetes ( 30718926) Waist circumference ( 25673412) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172)	Inflammatory bowel disease ( 23128233)
Interacting Genes		48 interacting genes: ACVR1 ANTKMT BMPR1B C19orf54 CADPS CERCAM CHCHD3 CTBP1 CTDSP1 CYB5R2 DDAH2 DOCK8 EIF4ENIF1 FAAP100 FANCB FANCD2 FANCF FANCI GATA1 GGN GRN HDHD3 HES1 HOXD4 ID2 IHO1 IKZF3 KIFC3 KRTAP11-1 KRTAP13-2 KRTAP19-6 LZTS2 METTL15 MORN3 PCNA RBM45 RIMBP3 RNF11 SCNM1 SNF8 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W UFSP1 YPEL3 ZNF581	19 interacting genes: AQP1 ARNT2 CATSPER1 CREB5 CTBP2 DGCR6 DGCR6L DTX2 EFHC1 FANCL MVP NOXA1 POLR1C PPIL1 PRKAA1 PRKAB2 TLE5 TRAF3IP2 ZNF488
Entrez ID		55120	85376
HPRD ID		06997	13881
Ensembl ID		ENSG00000115392	ENSG00000275793
Uniprot IDs		Q9NW38	Q9UFD9
PDB IDs		3ZQS 4CCG	2EGE
Enriched GO Terms of Interacting Partners?
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