AURKAIP1 and AJUBA

Number of citations of the paper that reports this interaction (PubMedID 13678582)
217

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		AURKAIP1	AJUBA
Description		aurora kinase A interacting protein 1	ajuba LIM protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Ribosome Intracellular Membrane-bounded Organelle	P-body Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Focal Adhesion Lamellipodium
	Molecular Function	Protein Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Alpha-catenin Binding Metal Ion Binding Actin Filament Binding
	Biological Process	MRNA Processing Negative Regulation Of Mitotic Nuclear Division Positive Regulation Of Proteolysis	Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Regulation Of Transcription, DNA-templated Cytoskeleton Organization Cell Cycle Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Regulation of PLK1 Activity at G2/M Transition Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Ulcerative colitis ( 28067908)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Insular cortex volume ( 31530798) Macular thickness ( 30535121) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Spatial processing ( 31596458)
Interacting Genes		6 interacting genes: ABHD4 AJUBA AURKA DEFB127 FAM9B GSK3A	20 interacting genes: ACTA1 AURKAIP1 AURKB BCAR1 CATSPER1 CREB5 CTNNA1 FARS2 GFI1B GRB2 LATS2 LCK LGALS14 PIN1 SLC1A2 TEKT3 TFAP4 TSG101 ZNF512B ZNF541
Entrez ID		54998	84962
HPRD ID		16457	16426
Ensembl ID		ENSG00000175756	ENSG00000129474
Uniprot IDs		Q9NWT8	Q96IF1
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K
Enriched GO Terms of Interacting Partners?
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