PPM1B and MYL7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PPM1B	MYL7
Description		protein phosphatase, Mg2+/Mn2+ dependent 1B	myosin light chain 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytosol Membrane	Cytosol Myosin Complex A Band Dendritic Spine
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Phosphatase Activity Protein Binding Manganese Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Calcium Ion Binding Protein Binding
	Biological Process	Protein Dephosphorylation N-terminal Protein Myristoylation Negative Regulation Of Interferon-beta Production Peptidyl-threonine Dephosphorylation Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Defense Response To Virus Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		ISG15 antiviral mechanism ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants	Smooth Muscle Contraction
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31152163) Height ( 23563607 31562340) Hip circumference adjusted for BMI ( 34021172) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258)	Fasting blood glucose ( 33842983) Offspring birth weight ( 31043758) Type 2 diabetes ( 32499647)
Interacting Genes		22 interacting genes: AATK CDK2 CDK6 ECHS1 EGFR ERBB3 ERBB4 IKBKB IKBKG KDR MAD2L2 MAP3K7 MSN MYL7 NCOA1 PPARG PTK7 ROR1 ROR2 RYK SIRPA VAV2	7 interacting genes: MCCD1 MEOX2 POU6F2 PPM1B PSORS1C2 SUOX TOX4
Entrez ID		5495	58498
HPRD ID		04796	10105
Ensembl ID		ENSG00000138032	ENSG00000106631
Uniprot IDs		O75688	Q01449
PDB IDs		2P8E
Enriched GO Terms of Interacting Partners?
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