CHCHD3 and DGKI

		CHCHD3	DGKI
Description		coiled-coil-helix-coiled-coil-helix domain containing 3	diacylglycerol kinase iota
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAM Complex Nucleus Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome MIB Complex	Nucleus Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Axon Synaptic Vesicle Membrane Protein-containing Complex Dendritic Spine Synapse Synaptic Membrane
	Molecular Function	Protein Binding Phosphatase Binding Molecular Adaptor Activity	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Lipid Phosphorylation Regulation Of Synaptic Transmission, Glutamatergic
Pathways		Mitochondrial protein import Cristae formation	Effects of PIP2 hydrolysis
Drugs			alpha-Tocopherol succinate
Diseases
GWAS		Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)	Adult body size ( 32376654) Adventurousness ( 30643258) AIDS progression ( 21502085) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26865924) Brain morphology (MOSTest) ( 32665545) Cognitive decline (age-related) ( 24468470) General risk tolerance (MTAG) ( 30643258) Lean body mass ( 28552196) Schizophrenia ( 28991256 25056061 29483656 30285260) Subcortical volume (MOSTest) ( 32665545) Testosterone levels in polycystic ovary syndrome ( 26284813)
Interacting Genes		40 interacting genes: AASS AMOTL2 ANKS1A ARMC7 BLZF1 C2CD6 CALCOCO2 CBY2 CCDC33 CCDC85B CEP72 CLPP CYSRT1 DGKI EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1	3 interacting genes: CHCHD3 RAB5C VHL
Entrez ID		54927	9162
HPRD ID		13044	07238
Ensembl ID		ENSG00000106554	ENSG00000157680
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	E7EWQ4 E9PFX6 O75912 Q59GE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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