CMTM6 and TMED8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CMTM6	TMED8
Description		CKLF like MARVEL transmembrane domain containing 6	transmembrane p24 trafficking protein family member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Early Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Transport Regulation Of Protein Stability Endocytic Recycling
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170) Cholesterol, total ( 24097068) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 32203549 28334899) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		24 interacting genes: APOA5 ATP13A2 BPIFA2 CD160 CD40 CIAO2A COQ8A DNMT3B DUSP10 DYNC1LI1 ECPAS EHHADH FAM9B MIEF1 PPBP RBFA RBMX RUSC1 SNRPB2 SPG21 SUMO2 TCEA2 TMED8 XRCC6	33 interacting genes: ADTRP AMIGO2 APOL2 ARL6IP1 C10orf67 CIAO2A CMTM5 CMTM6 CYB561D1 DEFB129 DERL1 DGAT2L6 EI24 H4C7 LAPTM4A MDK MMGT1 MRPL41 MRPS18B MTIF3 NDUFA12 PROX2 REEP6 SERP2 STX8 SUSD3 TMEM115 TMEM121 TMEM218 TMEM254 TRAM1L1 UNC50 ZDHHC16
Entrez ID		54918	283578
HPRD ID		06987	18201
Ensembl ID		ENSG00000091317	ENSG00000100580
Uniprot IDs		Q9NX76	Q6PL24
PDB IDs
Enriched GO Terms of Interacting Partners?
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