XAF1 and RNF114

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		XAF1	RNF114
Description		XIAP associated factor 1	ring finger protein 114
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Nucleus Cytosol Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Response To Interferon-beta	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Spermatogenesis Cell Differentiation
Pathways		Interferon alpha/beta signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP	29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1
Entrez ID		54739	55905
HPRD ID		06978	10329
Ensembl ID		ENSG00000132530	ENSG00000124226
Uniprot IDs		Q6GPH4	Q9Y508
PDB IDs		2LXW
Enriched GO Terms of Interacting Partners?
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