P4HTM and PDIA2

Number of citations of the paper that reports this interaction (PubMedID 12485997)
19

Data Source:
BioGRID (pull down)

		P4HTM	PDIA2
Description		prolyl 4-hydroxylase, transmembrane	protein disulfide isomerase family A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Calcium Ion Binding 2-oxoglutarate-dependent Dioxygenase Activity L-ascorbic Acid Binding	Protein Disulfide Isomerase Activity Steroid Binding Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Regulation Of Erythrocyte Differentiation	Protein Folding Protein Retention In ER Lumen Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress
Pathways
Drugs		Ascorbic acid
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		8 interacting genes: F2RL1 GLP1R GPR37 LTB4R2 PDIA2 QRICH1 RHOU UBC	12 interacting genes: ACTB CALR COL2A1 CUL3 GAPDH KRTAP12-1 KRTAP6-1 MAPT P4HTM PPARG SNCA SST
Entrez ID		54681	64714
HPRD ID		17842	07617
Ensembl ID		ENSG00000178467	ENSG00000185615
Uniprot IDs		Q9NXG6	Q13087
PDB IDs		6TP5
Enriched GO Terms of Interacting Partners?
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