RC3H2 and UBE2Q2

Number of citations of the paper that reports this interaction (PubMedID 26489670)
13

Data Source:
BioGRID (pull down)

		RC3H2	UBE2Q2
Description		ring finger and CCCH-type domains 2	ubiquitin conjugating enzyme E2 Q2
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GO Annotations	Cellular Component	P-body Cell Surface Cytoplasmic Stress Granule Membrane Intracellular Membrane-bounded Organelle	Nucleus Cytosol
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding MRNA Binding RNA Stem-loop Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay B Cell Homeostasis Ubiquitin-dependent Protein Catabolic Process Post-embryonic Development Multicellular Organism Growth T Cell Proliferation T Cell Homeostasis Lung Alveolus Development Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Limb Development T Follicular Helper Cell Differentiation Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process	Protein Polyubiquitination Protein K48-linked Ubiquitination
Pathways			Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)	Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Gout ( 33832965) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Triglyceride levels in HIV infection ( 33109212) Urate levels ( 31985003 23263486) Urate levels in obese individuals ( 25811787)
Interacting Genes		14 interacting genes: KLHL6 TRIM8 UBC UBE2B UBE2D2 UBE2E2 UBE2E3 UBE2G2 UBE2I UBE2K UBE2N UBE2Q2 UBE2V1 UBE2V2	10 interacting genes: BIRC2 BIRC3 ITCH MDM2 PCGF2 RC3H2 RNF111 RNF31 UBA1 UBC
Entrez ID		54542	92912
HPRD ID		14726	14294
Ensembl ID		ENSG00000056586	ENSG00000140367
Uniprot IDs		A0A024R899 Q9HBD1	Q8WVN8
PDB IDs		4Z30 4Z31 4ZLC 4ZLD	1ZUO
Enriched GO Terms of Interacting Partners?
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