RAB4B and EXOC5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		RAB4B	EXOC5
Description		RAB4B, member RAS oncogene family	exocyst complex component 5
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Secretory Granule Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome	Exocyst Cytoplasm Cytosol Midbody
	Molecular Function	Molecular_function G Protein Activity Protein Binding GTP Binding	Protein Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Glucose Import	Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport Protein Localization To Plasma Membrane Epithelial Cell Apoptotic Process Non-motile Cilium Assembly
Pathways		Neutrophil degranulation RAB geranylgeranylation MET receptor recycling	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Carotid intima media thickness (mean) ( 31801372) Chronic obstructive pulmonary disease ( 22080838 28166215) Emphysema imaging phenotypes ( 26030696) Eosinophil percentage of white cells ( 32888494) Hematocrit ( 32888494) Hemoglobin ( 32888494) Kawasaki disease ( 22081228) Red blood cell count ( 32888494) Smoking behaviour (cigarettes smoked per day) ( 30617275)	Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		9 interacting genes: BOLA2 BOLA2B CDC45 EXOC5 FAM71C RAB7A RABAC1 RABEP1 VPS52	46 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 GNB1 HDDC3 HGS ICA1 IFT57 KIAA0586 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2
Entrez ID		53916	10640
HPRD ID		11473	07258
Ensembl ID		ENSG00000167578	ENSG00000070367
Uniprot IDs		A0A024R0K8 P61018	O00471
PDB IDs		2O52
Enriched GO Terms of Interacting Partners?
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