PMP22 and CEACAM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PMP22	CEACAM3
Description		peripheral myelin protein 22	CEA cell adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Compact Myelin Synapse	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Population Proliferation Negative Regulation Of Neuron Projection Development Cell Differentiation Bleb Assembly Myelin Assembly
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination	Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		59 interacting genes: APOL3 ARL13B ASGR2 ATP6AP2 C16orf54 CANX CD3G CD53 CD69 CEACAM3 CLDN18 CLDN5 CLDN6 CLEC12B CLEC14A CREB3 CREB3L1 DDX52 EBP EDA EMP1 ERGIC3 FAM209A FCGRT FFAR2 GJA8 GPR42 GPR61 GPRC5D IFNGR2 KCNJ6 KCNN4 KLRC1 LMNA MPZ MS4A7 OPRM1 PDZK1IP1 PEX19 PGRMC2 REEP4 SCN3B SDC4 SHISAL1 SLC18A1 SLC38A1 SMIM3 SPACA1 STOM SYT2 TLCD4 TM4SF18 TM4SF19 TMEM139 TMEM14B TMEM30B TMEM31 TMX1 TSPAN12	8 interacting genes: CEACAM1 CNIH3 CSNK1A1L NINJ1 NINJ2 PMP22 S100A8 SRC
Entrez ID		5376	1084
HPRD ID		03059	16450
Ensembl ID		ENSG00000109099	ENSG00000170956
Uniprot IDs		A8MU75 Q01453 Q6FH25	P40198
PDB IDs			6AVZ 6AW0 6AW1 6AW3
Enriched GO Terms of Interacting Partners?
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