PMM1 and RCHY1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PMM1	RCHY1
Description		phosphomannomutase 1	ring finger and CHY zinc finger domain containing 1
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GO Annotations	Cellular Component	Cytosol Neuronal Cell Body	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Phosphomannomutase Activity Protein Binding Metal Ion Binding	P53 Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Mannose Metabolic Process Protein N-linked Glycosylation GDP-mannose Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Error-free Translesion Synthesis
Pathways		Synthesis of GDP-mannose	Translesion Synthesis by POLH Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Metabolite levels ( 23823483) Response to tocilizumab in rheumatoid arthritis ( 22491018)
Interacting Genes		6 interacting genes: CACNA1A MFHAS1 RAB6A RAB6B RBX1 RCHY1	75 interacting genes: ADAMTSL4 AIG1 ANGPTL8 AOX1 AR ARF4 ATN1 BIRC3 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CREB5 CYBA DAPK1 DCUN1D5 F7 FADS6 GFI1B GORAB HOXA1 HOXA2 HOXA3 HOXB1 HOXB2 HOXB5 HOXC11 HOXC4 HOXD10 HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NLA PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 WDR74 ZNF160
Entrez ID		5372	25898
HPRD ID		03473	07607
Ensembl ID		ENSG00000100417	ENSG00000163743
Uniprot IDs		A0A024R1U5 Q92871	Q96PM5
PDB IDs		2FUC 2FUE 6CFR 6CFS 6CFT 6CFU 6CFV	2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
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