PLEC and ANK3

  • Number of citations of the paper that reports this interaction (PubMedID 21223964)
  • 10
  • Data Source:
  • BioGRID (two hybrid, pull down, affinity chromatography technology)

PLEC

ANK3

Description plectin ankyrin 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Bipolar disorder ( 22182935 21926972 18711365 33263727 24618891 31043756 28072414 20351715)
  • Bipolar disorder or major depressive disorder ( 20351715)
  • Bipolar I disorder ( 31043756)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronotype ( 30696823)
  • Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Frailty index ( 34431594)
  • Heel bone mineral density ( 30598549)
  • Height ( 31562340)
  • Metabolite levels ( 23823483)
  • Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
  • Psychotic experience ( 31553412)
  • Refractive error ( 32231278)
  • Schizophrenia ( 20185149)
  • Third ventricle volume ( 31530798)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)
Interacting Genes 24 interacting genes: ACTC1 ACTG1 ANK3 BRCA2 CASP8 CDK1 COL17A1 EGFR ITGA6 ITGB4 LMNB1 MAP2 MSN MTDH PLEKHA5 PTEN RACK1 SMAD9 SNAPIN SPTA1 SPTAN1 SUMO2 UBC VIM 27 interacting genes: ENO1 FADD FAS FTH1 GABARAP GRM4 HOOK1 KCNC1 MAP1LC3A MAP1LC3C MAPK6 MBL2 NAB2 PIK3R1 PLEC POLR1G SCN1B SCN2A SCNN1B SGPL1 SMAD2 SMAD3 SPTBN4 SRPK2 TACR2 UBE2D1 XPNPEP1
Entrez ID 5339 288
HPRD ID 03180 02715
Ensembl ID ENSG00000178209 ENSG00000151150
Uniprot IDs Q15149 Q12955 Q8NAK2
PDB IDs 1MB8 2N03 2ODU 2ODV 3F7P 3PDY 3PE0 4GDO 4Q58 4Q59 5J1F 5J1G 5J1H 5J1I 4O6X
Enriched GO Terms of Interacting Partners?
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