LRP1B and SERPINE1

  • Number of citations of the paper that reports this interaction (PubMedID 11384978)
  • 43
  • Data Source:
  • HPRD (in vivo)

LRP1B

SERPINE1

Description LDL receptor related protein 1B serpin family E member 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Adventurousness ( 30643258)
  • Adverse response to drug ( 30420678)
  • Aging ( 19367585)
  • Asthma (childhood onset) ( 27611488)
  • Blood pressure (smoking interaction) ( 25189868)
  • Body mass index ( 28892062 25673413 20935630)
  • Body size at age 10 ( 32376654)
  • Cataracts ( 34127677)
  • Cerebellum white matter volume ( 31530798)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Cognitive performance (processing speed) ( 31598132)
  • Congenital heart disease (inherited effect) ( 28468790)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
  • Dietary fat liking ( 32516399)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Diisocyanate-induced asthma ( 25918132)
  • Erectile dysfunction and prostate cancer treatment ( 20932654)
  • Estimated glomerular filtration rate ( 31217584)
  • Facial attractiveness (male raters) ( 30946739)
  • General risk tolerance (MTAG) ( 30643258)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • Hepcidin/ferritin ratio ( 27846281)
  • Household income (MTAG) ( 31844048)
  • Influenza A (H1N1) infection ( 26379185)
  • Keratoconus ( 33649486)
  • Lung adenocarcinoma ( 28604730)
  • Menarche (age at onset) ( 21102462 25231870)
  • Mood instability ( 31168069)
  • Motion sickness ( 25628336)
  • Night sleep phenotypes ( 27126917)
  • Number of sexual partners ( 30643258)
  • Optic nerve measurement (disc area) ( 20395239)
  • Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627)
  • Periodontitis (CDC/AAP) ( 24024966)
  • Post bronchodilator FEV1 ( 26634245)
  • Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189)
  • Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
  • Severe influenza A (H1N1) infection ( 26379185)
  • Type 1 diabetes ( 32005708)
  • Type 2 diabetes ( 30130595)
  • Blood protein levels ( 30072576)
  • Nonunion in individuals with fractures ( 30680360)
  • Plasma plasminogen activator levels ( 24578379)
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Interacting Genes 8 interacting genes: APP EVL FGA LRPAP1 PABPC1 PLAT PLAUR SERPINE1 26 interacting genes: ACTN4 DYNC1I1 ELANE F2 HSD17B11 IGFBP5 KLK2 KRT18 LMNA LRP1 LRP1B LRP2 MMP3 ORM1 PITX1 PLAT PLAU PLG SGTA SGTB TLX3 TMEM237 UBQLN1 UBQLN2 UBQLN4 VTN
Entrez ID 53353 5054
HPRD ID 16383 01418
Ensembl ID ENSG00000168702 ENSG00000106366
Uniprot IDs Q9NZR2 A0A024QYT5 P05121
PDB IDs 1A7C 1B3K 1C5G 1DB2 1DVM 1DVN 1LJ5 1OC0 3CVM 3EOX 3PB1 3Q02 3Q03 3R4L 3UT3 4AQH 4G8O 4G8R 4IC0 5BRR 5ZLZ 6GWN 6GWP 6GWQ 6I8S 6ZRV 7AQF 7AQG 9PAI
Enriched GO Terms of Interacting Partners?
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