PKNOX1 and BORCS6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PKNOX1	BORCS6
Description		PBX/knotted 1 homeobox 1	BLOC-1 related complex subunit 6
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Lysosomal Membrane BORC Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Identical Protein Binding
	Biological Process	Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II T Cell Differentiation Erythrocyte Differentiation Camera-type Eye Development Positive Regulation Of Transcription By RNA Polymerase II	Lysosome Localization
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Biochemical measures ( 19260141) Blood and toenail selenium levels ( 25343990) Cognitive performance ( 20125193) Information processing speed ( 21130836)
Interacting Genes		26 interacting genes: APP BLOC1S5 BORCS6 FAM110B FHL2 HMGB2 HOXA1 HOXB6 HOXB7 HOXD9 MEIS1 MPP3 MX2 NUP58 PAX6 PBX1 PBX2 PBX4 PCNT POU2F1 RFX3 TET2 TLX1 UBR1 VPS37C ZBTB3	35 interacting genes: ABI2 BEX2 C19orf25 C1orf109 C1orf216 DISC1 EPS8 EXOC8 EXOSC5 FAM161B FAM9C FBXO44 FCHSD2 GAS8 HAUS1 HGS INSYN1 KANK2 KXD1 LAMTOR2 LNX1 MED21 MOS NDEL1 NTAQ1 OSTF1 PKNOX1 PLA2G4A RCOR3 RIBC1 SHPRH SPG21 TACC2 USHBP1 ZNF655
Entrez ID		5316	54785
HPRD ID		03653	13368
Ensembl ID		ENSG00000160199	ENSG00000196544
Uniprot IDs		B4DGV5 E7EPN6 P55347 Q6PKH2 Q96I87	Q96GS4
PDB IDs		1X2N
Enriched GO Terms of Interacting Partners?
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