PIP4K2A and RPS6KB1

  • Number of citations of the paper that reports this interaction (PubMedID 12747804)
  • 11
  • Data Source:
  • BioGRID (enzymatic study)

PIP4K2A

RPS6KB1

Description phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ribosomal protein S6 kinase B1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (B-cell precursor) ( 23996088)
  • Acute lymphoblastic leukemia (childhood) ( 29348612)
  • Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299)
  • B-cell acute lymphoblastic leukaemia ( 31767839)
  • Height ( 31562340)
  • Lymphocyte percentage of white cells ( 32888494)
  • Obesity-related traits ( 23251661)
  • Positive urgency ( 30718321)
  • Severe influenza A (H1N1) infection ( 26379185)
  • Body shape index ( 34021172)
  • C-reactive protein levels ( 30388399)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Chronic lymphocytic leukemia or multiple sclerosis ( 31407831)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 23128233)
  • Multiple sclerosis ( 21833088)
  • Obesity-related traits ( 23251661)
  • Triglycerides ( 30275531)
Interacting Genes 7 interacting genes: BTK GSTK1 MEIS3 ODAD2 RAC1 RPS6KB1 TEC 62 interacting genes: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B CYB5R3 DEPTOR DPPA4 EEF2K EIF3B EIF3F EIF4B EIF4EBP1 EP300 FBXO7 GDI2P1 GRIA1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MARK2 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 PIP4K2A POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RPS6 RPTOR SRC STK11 SYK TBK1 TERT TRAF4 URI1 USP11 XPO1
Entrez ID 5305 6198
HPRD ID 11931 10202
Ensembl ID ENSG00000150867 ENSG00000108443
Uniprot IDs P48426 P23443
PDB IDs 2YBX 6OSP 6UX9 3A60 3A61 3A62 3WE4 3WF5 3WF6 3WF7 3WF8 3WF9 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 4RLO 4RLP 5WBH 5WBK
Enriched GO Terms of Interacting Partners?
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