ATP5PF and INPP5K

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP5PF	INPP5K
Description		ATP synthase peripheral stalk subunit F6	inositol polyphosphate-5-phosphatase K
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Cell Surface	Ruffle Nucleus Cytoplasm Endoplasmic Reticulum Trans-Golgi Network Cytosol Plasma Membrane Membrane Ruffle Membrane Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein-containing Complex Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Vasopressin Receptor Activity Protein Binding Inositol Bisphosphate Phosphatase Activity Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Phosphatidylinositol Trisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Lipid Phosphatase Activity Inositol Trisphosphate Phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Positive Regulation Of Heart Rate Response To Muscle Activity Substantia Nigra Development Negative Regulation Of Prostaglandin Secretion Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Blood Pressure Negative Regulation Of Arachidonic Acid Secretion	In Utero Embryonic Development Negative Regulation Of Protein Phosphorylation Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Protein Kinase Activity Phosphatidylinositol Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Glucose Transmembrane Transport Dephosphorylation Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Dephosphorylation Positive Regulation Of Urine Volume Glucose Homeostasis Negative Regulation Of MAP Kinase Activity Negative Regulation By Host Of Viral Transcription Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Calcium Ion Transport Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of Protein Targeting To Membrane Ruffle Assembly Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Renal Water Transport
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Mean platelet volume ( 27863252)
Interacting Genes		18 interacting genes: ABHD16A ATP5F1B BCL2L2 INPP5K KCNK5 MALL MAPK6 MIEF1 MIEF2 MOSPD3 NDRG4 PHOSPHO2 PLP2 PTPN9 REEP6 RPS6KA3 SFT2D2 SIGLEC12	24 interacting genes: ANXA7 ARL6IP1 ATP5PF BDNF CDKN1A CPTP FADS6 FATE1 FBXO7 GOLT1B HMOX2 HSPB1 KRT31 MAD2L1BP NCOR2 PBX3 PFDN1 SFT2D2 SMG6 SMN1 TANK TK1 TNFRSF10D TTR
Entrez ID		522	51763
HPRD ID		04399	08489
Ensembl ID		ENSG00000154723	ENSG00000132376
Uniprot IDs		P18859 Q6IB54 Q6NZ59	B7Z4V9 Q9BT40
PDB IDs
Enriched GO Terms of Interacting Partners?
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