PFN2 and ANTKMT

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PFN2	ANTKMT
Description		profilin 2	adenine nucleotide translocase lysine methyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Extracellular Exosome	Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Actin Binding Actin Monomer Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP Hydrolysis Activity	Protein Binding Protein-lysine N-methyltransferase Activity
	Biological Process	Negative Regulation Of Epithelial Cell Migration Actin Cytoskeleton Organization Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of ATPase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Protein Stabilization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Ruffle Assembly	Peptidyl-lysine Trimethylation Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Signaling by ROBO receptors RHO GTPases Activate Formins RHO GTPases Activate Formins
Drugs		Triglyme Pentaglyme
Diseases
GWAS		Fish- and plant-related diet ( 32066663)
Interacting Genes		34 interacting genes: ACTB ACTG1 ANTKMT BIRC2 CCDC113 DDX11 DLST DNM1 EEF1A1 ERCC6 EVL FHOD1 FLT3LG FMNL1 GOLGB1 HTT IK IVNS1ABP MSANTD3 MYPOP NDUFB8 PLAUR PTPRS RAP1GAP RNF146 ROCK1 RPS10 SEPTIN5 SGTA SNTA1 SYN1 TERF1 VASP WDR33	24 interacting genes: BAG6 BANP C1orf109 CCDC24 DTX2 EFCAB2 FANCL HAP1 HDAC7 HGS IMMT KAT5 LUC7L LUC7L2 MEIS2 MGAT5B MKRN3 PARVG PFN2 PIK3R3 PPP1R16A SH3GL3 TP53 ZNF76
Entrez ID		5217	65990
HPRD ID		01451	14500
Ensembl ID		ENSG00000070087	ENSG00000103254
Uniprot IDs		P35080	J3KMW5 Q9BQD7
PDB IDs		1D1J
Enriched GO Terms of Interacting Partners?
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