PFKM and ATP6V0A4

Number of citations of the paper that reports this interaction (PubMedID 12649290)
43

Data Source:
HPRD (in vitro, in vivo)

		PFKM	ATP6V0A4
Description		phosphofructokinase, muscle	ATPase H+ transporting V0 subunit a4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol 6-phosphofructokinase Complex Membrane Apical Plasma Membrane Sperm Principal Piece	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Integral Component Of Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Brush Border Membrane Apical Part Of Cell Extracellular Exosome
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Protein C-terminus Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	Protein Binding Proton Transmembrane Transporter Activity ATPase Binding
	Biological Process	Glycogen Catabolic Process Fructose 6-phosphate Metabolic Process Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Insulin Secretion Glucose Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Muscle Cell Cellular Homeostasis Carbohydrate Phosphorylation Glycolytic Process Through Fructose-6-phosphate Canonical Glycolysis Glycolysis From Storage Polysaccharide Through Glucose-1-phosphate	Ossification Regulation Of PH Vacuolar Acidification Excretion Sensory Perception Of Sound Proton Transmembrane Transport
Pathways		Glycolysis	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494) Longevity (90 years and older) ( 25199915) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Pulse pressure ( 30578418) Red blood cell count ( 32888494)	F-cell distribution in sickle cell anaemia ( 21326311) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
Interacting Genes		19 interacting genes: ATP6V0A4 CAV3 DLC1 DYNLL1 FHL2 HGS LSM7 MAPK3 NDUFB2 NOS1 PCNA PDGFRL PFKL SFRP2 SFRP4 SIAH1 SUMO2 TEAD4 UBTD1	2 interacting genes: CYTH2 PFKM
Entrez ID		5213	50617
HPRD ID		01988	05576
Ensembl ID		ENSG00000152556	ENSG00000105929
Uniprot IDs		A0A024R0Y5 A0A2R8Y891 P08237	A0A024R791 Q9HBG4
PDB IDs		4OMT
Enriched GO Terms of Interacting Partners?
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