PFKFB4 and LRR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PFKFB4	LRR1
Description		6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	leucine rich repeat protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	6-phosphofructo-2-kinase Activity Fructose-2,6-bisphosphate 2-phosphatase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Fructose Metabolic Process Fructose 2,6-bisphosphate Metabolic Process Dephosphorylation Carbohydrate Phosphorylation	Protein Ubiquitination
Pathways		Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester Fructose-6-phosphate
Diseases
GWAS		Bitter beverage consumption ( 31046077) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Mental health study participation (completed survey) ( 31263887) Morning person ( 30696823) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908 25082827) Waist-hip index ( 34021172)
Interacting Genes		8 interacting genes: CCDC102B CDC23 CSNK2B GADD45A GSK3B LRR1 PFKFB1 PJA1	7 interacting genes: CDKN1A MTUS2 PFKFB4 PNMA2 TNFRSF9 TRIP13 UBE2D1
Entrez ID		5210	122769
HPRD ID		05613	15164
Ensembl ID		ENSG00000114268	ENSG00000165501
Uniprot IDs		B7Z5C3 Q16877 Q5XLC3 Q66S35	A0A384MTQ0 Q6AWA7 Q96L50
PDB IDs
Enriched GO Terms of Interacting Partners?
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