MAP3K20 and ZFP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MAP3K20	ZFP1
Description		mitogen-activated protein kinase kinase kinase 20	ZFP1 zinc finger protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus
	Molecular Function	Magnesium Ion Binding RNA Binding MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Damage Checkpoint Signaling Protein Phosphorylation Cytoskeleton Organization Cell Cycle JNK Cascade Cell Death Cell Differentiation P38MAPK Cascade Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Regulation Of Cell Cycle Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs		Dasatinib Fostamatinib
Diseases
GWAS		Haemorrhoidal disease ( 33888516)	Alcoholic chronic pancreatitis ( 28754779) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Pancreatic cancer ( 25086665)
Interacting Genes		32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775	22 interacting genes: CARD10 CAVIN1 CCDC125 CCDC136 CEP19 CEP70 CIB3 CRLF3 EMD GOLGA6L9 HAP1 HOOK2 KRT40 LDOC1 MAP3K20 MFAP1 MTUS2 POU6F2 TBC1D1 TRIM41 TSPYL2 ZNF250
Entrez ID		51776	162239
HPRD ID		11791	15724
Ensembl ID		ENSG00000091436	ENSG00000184517
Uniprot IDs		D4Q8H0 Q9NYL2	H3BV40 J3KNQ1 Q6P2D0
PDB IDs		5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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