WBP11 and TESC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		WBP11	TESC
Description		WW domain binding protein 11	tescalcin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Intracellular Membrane-bounded Organelle	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Ruffle Membrane
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	RRNA Processing MRNA Cis Splicing, Via Spliceosome	Negative Regulation Of Cell Population Proliferation Male Gonad Development Positive Regulation Of Gene Expression Protein Transport Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of Catalytic Activity Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Localization To Plasma Membrane
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Mean platelet volume ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Total hippocampal volume ( 30279459)
Interacting Genes		33 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 CYGB DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 MORN4 NCK2 NOD2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SEC23A SRC TESC TRAF4 TRIP10 UBASH3A VIM WBP4	7 interacting genes: CCDC91 DYNLT3 HMG20A RAI1 RPL36 SLC9A1 WBP11
Entrez ID		51729	54997
HPRD ID		18293	11649
Ensembl ID		ENSG00000084463	ENSG00000088992
Uniprot IDs		A0A024RAW9 Q9Y2W2	Q96BS2
PDB IDs		7ABF 7ABG
Enriched GO Terms of Interacting Partners?
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