LSM8 and FERMT3

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		LSM8	FERMT3
Description		LSM8 homolog, U6 small nuclear RNA associated	FERM domain containing kindlin 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex	Podosome Extracellular Region Membrane Cell-substrate Junction Platelet Alpha Granule Lumen Cell Projection Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	Integrin Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process	Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell Migration Integrin Activation Regulation Of Cell-cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Platelet Aggregation
Pathways		mRNA Splicing - Major Pathway	Platelet degranulation
Drugs
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 33627673 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 33082346) Smoking status (current vs never) ( 33082346) Triglyceride levels ( 30108155)	Attention deficit hyperactivity disorder ( 21784300) Crohn's disease ( 28067908) Fruit consumption ( 32066663) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401)
Interacting Genes		49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	11 interacting genes: ANKRD29 APP EXOSC10 ILK ITGB1 LIMS1 LSM8 PARVA PRPF18 TINF2 TRIM15
Entrez ID		51691	83706
HPRD ID		06288	07440
Ensembl ID		ENSG00000128534	ENSG00000149781
Uniprot IDs		A4D0W0 O95777	Q86UX7
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG	2YS3 6V97 6V9G 7C3M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?