TMEM14C and ELOVL7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM14C	ELOVL7
Description		transmembrane protein 14C	ELOVL fatty acid elongase 7
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Regulation Of Heme Biosynthetic Process	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways			Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)	Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)
Interacting Genes		46 interacting genes: ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SDC3 SHANK3 SLC10A6 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27	12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1
Entrez ID		51522	79993
HPRD ID		15524	18700
Ensembl ID		ENSG00000111843	ENSG00000164181
Uniprot IDs		A0A024R001 Q9P0S9	A1L3X0 D6RHD0
PDB IDs		2LOS	6Y7F
Enriched GO Terms of Interacting Partners?
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