PDE4B and PRKACA

  • Number of citations of the paper that reports this interaction (PubMedID 12441002)
  • 14
  • Data Source:
  • HPRD (in vivo)

PDE4B

PRKACA

Description phosphodiesterase 4B protein kinase cAMP-activated catalytic subunit alpha
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 22076464 23007406)
  • Adult body size ( 32376654)
  • Age at first birth ( 34211149)
  • Age at first sexual intercourse ( 34211149)
  • Age at voice drop ( 27182965)
  • Alanine aminotransferase levels ( 33547301)
  • Alcohol consumption ( 31358974)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety and stress-related disorders ( 31116379)
  • Anxiety and stress-related disorders (excluding adjustment disorder) ( 31116379)
  • Anxiety and stress-related disorders (excluding co-morbid schizophrenia) ( 31116379)
  • Anxiety and stress-related disorders (including obsessive-compulsive disorder) ( 31116379)
  • Anxiety and stress-related disorders (psychiatric co-morbidity covariate model) ( 31116379)
  • Anxiety and stress-related disorders (psychiatric co-morbidity weighting design) ( 31116379)
  • Anxiety disorders ( 31116379)
  • Aspartate aminotransferase levels ( 33547301)
  • Birth weight ( 31043758)
  • Body size at age 10 ( 32376654)
  • C-reactive protein levels ( 33339817)
  • Chronotype ( 30696823)
  • Echocardiographic traits ( 17903301)
  • Economic and political preferences (feminism/equality) ( 22566634)
  • Fibrinogen levels ( 28107422)
  • Gastroesophageal reflux disease ( 31527586)
  • Low tan response ( 29739929)
  • Multiple sclerosis ( 31604244)
  • Phenylephrine infusion rate during anesthesia ( 31455332)
  • Problematic alcohol use ( 32451486)
  • QT interval ( 29213071)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Sleep duration (short sleep) ( 30846698)
  • Smoking initiation ( 30617275 33082346)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Staphylococcus aureus infection ( 24847357)
  • Stress-related disorders ( 31116379)
Interacting Genes 6 interacting genes: DISC1 MAGEA11 PRKACA RCBTB2 SLIT2 SMURF2 219 interacting genes: AANAT ABCA1 ACLY ADCY5 ADD1 ADD2 AKAP1 AKAP14 AKAP8L AKIP1 ANXA7 APC APOBEC3G ARFGEF3 ASIC1 ASIC3 ATF1 ATP2B1 AURKA AVPI1 BAD BCL2 BFAR BRAF CACNA1C CACNB2 CACNG2 CAD CALD1 CAMKK2 CCDC88A CCND1 CD46 CDK16 CDKN1A CETN1 CFTR CIITA CLDN3 CLTC CREB1 CREM CRK CSK CUL5 CYP3A4 DMTN DNAJC5 DOCK1 DRD1 DSP EEF2K EGFR ELL ERBB3 ESR1 ETV1 FBXW11 FOS FXYD1 GABRB3 GABRR1 GAD1 GAD2 GFAP GJA5 GJB1 GLI1 GMFB GNA13 GNMT GP1BB GRIA1 GRIA4 GRK2 GSK3A GSK3B GUSB GYS1 HAND1 HAND2 HDAC1 HDAC8 HIF1A HMGCR HMGN1 HMGN2 HNF4A HNRNPD HSP90AA1 HSPA4 HSPD1 IFNAR1 IQGAP1 IRF2 ITCH ITGA2B ITGA4 ITPKA ITPKB ITPR1 ITPR2 KCNH2 KCNJ12 KCNQ1 KDELR1 KLF1 KLHL3 LCK LCP1 LIPE LRP1 MAP2 MAP3K3 MAPT MBP MC4R MECP2 MEF2D MEP1B MGMT MIP NDRG1 NFKB1 NIN NOLC1 NOS1 NOXA1 NR3C1 NSFL1C NUP85 PARK7 PDC PDE3A PDE3B PDE4B PDE4D PDPK1 PFKFB1 PFKFB2 PHKA1 PHOX2A PKIA PKIB PLIN1 PLN POU2F1 PPP1R10 PPP1R17 PPP1R1B PPP1R8 PPP1R9B PRKAR1A PRKAR1B PRKCA PSEN1 PSMD11 PTBP1 PTPN12 PTPN13 PTPN7 PTPRR RAB8A RAF1 RALBP1 RANBP9 RANGAP1 RAP1A RAP1B RAP1GAP RASGRF1 RASGRP3 RELA RFX1 RGS10 RGS13 RGS14 RHOA RRAD RSBN1 RYR1 RYR2 SI SIK1 SIK3 SLC2A2 SLC4A4 SLC9A3R2 SNAP25 SNAPIN SNPH SPTBN1 SRC STK11 STMN1 STMN2 STUB1 SYN1 SYN2 TCF4 TH THOP1 TNP1 TNP2 TPH1 TPM4 TRIM55 TRIM63 TRIP10 UBE3A UHRF1 USP20 UTRN VASP VIM VTN WT1 YWHAZ ZNF208
Entrez ID 5142 5566
HPRD ID 02528 03382
Ensembl ID ENSG00000184588 ENSG00000072062
Uniprot IDs Q07343 Q59GM8 Q68CX5 X5DNX5 X5DR82 A0A024R7J0 A8K8B9 P17612
PDB IDs 1F0J 1JP1 1JP2 1RO6 1RO9 1ROR 1TB5 1XLX 1XLZ 1XM4 1XM6 1XMU 1XMY 1XN0 1XOS 1XOT 1Y2H 1Y2J 2CHM 2QYL 3D3P 3FRG 3G45 3GWT 3HC8 3HDZ 3HMV 3KKT 3LY2 3O0J 3O56 3O57 3W5E 3WD9 4KP6 4MYQ 4NW7 4WZI 4X0F 5K6J 5LAQ 5OHJ 6BOJ 2GU8 3AGL 3AGM 3AMA 3AMB 3L9L 3L9M 3L9N 3MVJ 3NX8 3OOG 3OVV 3OWP 3OXT 3P0M 3POO 3VQH 4AE6 4AE9 4UJ1 4UJ2 4UJ9 4UJA 4UJB 4WB5 4WB6 4WB7 4WB8 5BX6 5BX7 5IZF 5IZJ 5J5X 5N23 5UZK 6BYR 6BYS 6C0U 6FRX 6NO7 6QJ7 6WJF 6WJG
Enriched GO Terms of Interacting Partners?
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