TRPV2 and TRPV1

Number of citations of the paper that reports this interaction (PubMedID 16115206)
39

Data Source:
HPRD (in vivo)

		TRPV2	TRPV1
Description		transient receptor potential cation channel subfamily V member 2	transient receptor potential cation channel subfamily V member 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Growth Cone Membrane Melanosome Axonal Growth Cone Cell Body	Mitochondrion Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Neuronal Cell Body Postsynaptic Membrane
	Molecular Function	Ion Channel Activity Cation Channel Activity Calcium Channel Activity Ion Transmembrane Transporter Activity	Transmembrane Signaling Receptor Activity Ion Channel Activity Extracellular Ligand-gated Ion Channel Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Voltage-gated Calcium Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Calcium-release Channel Activity Chloride Channel Regulator Activity Phosphatidylinositol Binding Identical Protein Binding Metal Ion Binding Phosphoprotein Binding Temperature-gated Ion Channel Activity
	Biological Process	Sensory Perception Response To Temperature Stimulus Response To Heat Positive Regulation Of Axon Extension Calcium Ion Transmembrane Transport Positive Regulation Of Calcium Ion Import Calcium Ion Import Across Plasma Membrane Positive Regulation Of Cold-induced Thermogenesis	Negative Regulation Of Transcription By RNA Polymerase II Fever Generation Microglial Cell Activation Diet Induced Thermogenesis Peptide Secretion Negative Regulation Of Systemic Arterial Blood Pressure Lipid Metabolic Process Cell Surface Receptor Signaling Pathway Chemosensory Behavior Negative Regulation Of Heart Rate Negative Regulation Of Mitochondrial Membrane Potential Glutamate Secretion Cellular Response To Heat Positive Regulation Of Apoptotic Process Response To Peptide Hormone Positive Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Sensory Perception Of Mechanical Stimulus Thermoception Detection Of Temperature Stimulus Involved In Thermoception Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Excitatory Postsynaptic Potential Smooth Muscle Contraction Involved In Micturition Positive Regulation Of Gastric Acid Secretion Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Tumor Necrosis Factor Cellular Response To Acidic PH Cellular Response To Temperature Stimulus Negative Regulation Of Establishment Of Blood-brain Barrier Calcium Ion Import Across Plasma Membrane Response To Capsazepine Cellular Response To Nerve Growth Factor Stimulus
Pathways		TRP channels	TRP channels
Drugs		Cannabidiol Tetrahydrocannabivarin Medical Cannabis Nabiximols Cannabidivarin	alpha-Linolenic acid Icosapent Aspartame Tramadol Acetaminophen Camphor Ricinoleic Acid Resiniferatoxin Capsaicin Cannabidiol Zucapsaicin Propacetamol Capsicum oleoresin Nonivamide (S)-camphor Medical Cannabis Nabiximols Cannabidivarin
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		2 interacting genes: SLC50A1 TRPV1	9 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2 TUBD1
Entrez ID		51393	7442
HPRD ID		05980	03648
Ensembl ID		ENSG00000187688	ENSG00000196689
Uniprot IDs		Q9Y5S1	Q8NER1
PDB IDs		2F37	6L93
Enriched GO Terms of Interacting Partners?
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