MS4A4A and NRG1

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

MS4A4A

NRG1

Description membrane spanning 4-domains A4A neuregulin 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 21460841)
  • Alzheimer's disease in APOE e4- carriers ( 25778476)
  • C-reactive protein levels ( 30388399)
  • Cerebrospinal fluid sTREM-2 levels ( 31413141)
  • Fibrinogen levels ( 28107422)
Interacting Genes 14 interacting genes: ATP6V0E1 CLDN19 CMTM7 LPAR3 MAL NRG1 PLP1 RPRM RUSF1 SEC22A SERTM1 TMEM14B TMUB2 UPK1B 23 interacting genes: ADAM19 ADGRA2 ASGR2 CD72 CEBPD DKK4 EGF EGFR EIF4EBP1 ERBB2 ERBB3 ERBB4 FGFR1 IKZF4 ISG20 JAGN1 KCNK4 LAPTM4B LIMK1 LIPF MS4A4A PLP1 TMEM54
Entrez ID 51338 3084
HPRD ID 08408 00802
Ensembl ID ENSG00000110079 ENSG00000157168
Uniprot IDs A0A384MDW1 Q4JF27 Q96JQ5 A0A024QY88 A0A494C0K4 A0A494C0L9 A0A494C0Q4 A0A494C114 A0A494C1B5 A0A494C1F5 A0A494C1F8 A5YAK6 A5YAK8 A6MW54 A6MW55 A6MW56 B0FWZ3 B0FYA7 B0FYA8 B0FYA9 B7Z1D7 B7Z1E3 E3SFM9 F6RJN6 Q02297 Q6PK61 Q7RTW3 Q7RTW5
PDB IDs 1HAE 1HAF 1HRE 1HRF 3U7U
Enriched GO Terms of Interacting Partners?
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