SPG21 and RPS19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPG21	RPS19
Description		SPG21 abhydrolase domain containing, maspardin	ribosomal protein S19
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle	Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Postsynaptic Density Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Protein Binding CD4 Receptor Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Fibroblast Growth Factor Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Antigen Receptor-mediated Signaling Pathway	Ribosomal Small Subunit Assembly Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Cytoplasmic Translation Monocyte Chemotaxis RRNA Processing Translation Nucleolus Organization Response To Extracellular Stimulus Erythrocyte Differentiation Maturation Of SSU-rRNA Killing Of Cells Of Other Organism Ribosomal Small Subunit Biogenesis Defense Response To Gram-negative Bacterium Positive Regulation Of Cellular Component Movement Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545)
Interacting Genes		164 interacting genes: - ACOT13 AGTR1 AGTRAP AKIRIN2 APOC1 ARL6IP1 ARL8A ARMC12 ARMC7 ATP5ME ATPAF2 BORCS6 BSND C10orf82 C9orf24 CCDC102B CCDC153 CCDC33 CCHCR1 CD4 CDK2AP1 CDKN2B CEP76 CEPT1 CFAP410 CIDEB CLDN22 CMTM4 CMTM5 CMTM6 COG3 COG6 CPSF7 CRX CRYAA CT55 CTIF CTPS2 CUTC DCTPP1 DTX2 DTX3L EFHC2 EIF1B EIF4H EYA2 FAM114A1 FAM86C1P FBXO44 FLACC1 GAD2 GAS8 GEMIN2 GEMIN4 GGA2 GOLGA2 GOLT1B GRPEL1 GSK3A HNRNPH1 HPRT1 HSD17B13 IKZF3 INCA1 IQCB1 KCTD9 KRT13 KRT15 KRT19 KRT31 LEPROTL1 LMNA LMO1 LNX1 LSMEM2 MAB21L3 MID2 MPC2 MTMR9 MTUS2 MYG1 MYOG N4BP3 NAB2 NDUFAF2 NIF3L1 NME4 NQO2 NR1D1 NRDE2 NUP54 PAX6 PBX4 PCBD2 PCNA PDE5A PEF1 PFDN5 PLP2 PNMA5 PPM1J PRPS1 PRTFDC1 PSMB4 PTPA RABAC1 RAD51C REEP6 REL ROPN1 RPRD1B RPS19 RTL8B RTN4 S100B SATB1 SCAMP1 SEPTIN5 SFT2D1 SH3GL1 SLC35E3 SORBS3 SPRED1 SPRED2 SRGAP2B SSBP4 SWSAP1 SYNGR1 SYNGR3 SYP TCF12 TCF4 TEKT4 TFG TFIP11 TLE5 TMEM208 TMEM239 TOX2 TPD52 TRAF1 TRAF2 TRIB3 TRIM14 TRIM23 TRIM50 TRIM54 TRIM9 TSGA10IP TSNAXIP1 TTC23L TXN TXNL4B UFSP1 USHBP1 VMAC VPS25 YPEL3 ZBTB42 ZMYND12 ZNF263 ZNF581 ZNF629	8 interacting genes: APP C5AR1 FGF2 GSK3A PSMD8 RPS19BP1 SPG21 TXNDC11
Entrez ID		51324	6223
HPRD ID		10492	04591
Ensembl ID		ENSG00000090487	ENSG00000105372
Uniprot IDs		A0A024R5Y1 Q9NZD8	B0ZBD0 P39019
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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