REEP2 and CYP4F22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		REEP2	CYP4F22
Description		receptor accessory protein 2	cytochrome P450 family 4 subfamily F member 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Integral Component Of Plasma Membrane Membrane Endoplasmic Reticulum Tubular Network	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Microtubule Binding Taste Receptor Binding	Monooxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Heme Binding
	Biological Process	Regulation Of Intracellular Transport Protein Transport Into Membrane Raft Sensory Perception Of Bitter Taste Sensory Perception Of Sweet Taste Endoplasmic Reticulum Tubular Network Organization	Icosanoid Metabolic Process Ceramide Biosynthetic Process
Pathways		Olfactory Signaling Pathway	Fatty acids Miscellaneous substrates Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX) Defective CYP4F22 causes ARCI5
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061)	Lymphocyte counts ( 32888494)
Interacting Genes		25 interacting genes: BNIP3 C2CD2L CMTM5 CYP4F2 CYP4F22 ITGAM KDM3B MS4A1 MUL1 NAT8 ORMDL3 RABAC1 SCD SFT2D2 SLC25A46 TMBIM6 TMEM120B TMEM208 TMEM239 TMEM31 TMEM42 TMEM60 TMX2 TTPA YIF1A	4 interacting genes: AQP6 MSMO1 REEP2 TLCD4
Entrez ID		51308	126410
HPRD ID		16655	08256
Ensembl ID		ENSG00000132563	ENSG00000171954
Uniprot IDs		A8K3D2 Q9BRK0	Q6NT55
PDB IDs
Enriched GO Terms of Interacting Partners?
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