CDK18 and CCDC88B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDK18	CCDC88B
Description		cyclin dependent kinase 18	coiled-coil domain containing 88B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Membrane
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Binding Microtubule Binding Dynein Light Intermediate Chain Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Regulation Of Cell Cycle	Positive Regulation Of Cytokine Production Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Positive Regulation Of T Cell Proliferation Defense Response To Protozoan Positive Regulation Of T Cell Activation
Pathways
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241)	Basal cell carcinoma ( 31174203 33549134) Crohn's disease ( 28067908) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Inflammatory bowel disease ( 23128233) Keratinocyte cancer (MTAG) ( 31174203) Leprosy ( 25642632) Medication use (thyroid preparations) ( 31015401) Primary biliary cholangitis ( 26394269) Primary sclerosing cholangitis ( 27992413) Sarcoidosis ( 22837380) Triglyceride levels ( 32154731) Type 1 diabetes ( 34127860) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		58 interacting genes: AK8 APP BLZF1 CBY2 CCDC102B CCDC125 CCDC85B CCDC88B CCND3 CCNDBP1 CCNK CEP76 DNAH2 EYA2 FSD2 GOLGA2 GOLGA6L9 GORASP2 HAP1 HMBOX1 HOMER3 HOOK2 INCA1 KIFC3 KRT15 KRT16 KRT31 KRT34 KRT40 KRT75 KRT86 LZTS2 MAD1L1 MID2 MIPOL1 MTUS2 NUTM1 PIBF1 PNMA1 PPFIA1 PTPRC RABEP1 REL SEC23A TRAF1 TRAF2 TRIM27 TRIM50 TRIM54 TSGA10 TTC23 VPS28 VPS52 YWHAQ ZNF426 ZNF438 ZNF774 ZRANB1	41 interacting genes: BEX2 C1orf109 CARD9 CCHCR1 CDK18 CWF19L2 DEF6 DTNB EXOSC5 FAM161A FAM161B GEM HCK HOXB5 JAKMIP2 KANK2 LMNB1 LMNB2 LMO1 LNX1 NME7 PBX2 PIN1 PLEKHA5 PPP1R18 RALBP1 RBM7 RINT1 SH2D4A SH3KBP1 SRPK2 TBC1D22B TRAF3IP3 TSC1 TSG101 TSGA10 TSGA10IP TSHZ2 TXLNB USP2 ZC2HC1C
Entrez ID		5129	283234
HPRD ID		01354	10986
Ensembl ID		ENSG00000117266	ENSG00000168071
Uniprot IDs		A0A024R980 A0A024R996 Q07002 Q59G02	A6NC98 B2RTU8
PDB IDs
Enriched GO Terms of Interacting Partners?
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