MARCHF2 and STX6

Number of citations of the paper that reports this interaction (PubMedID 15689499)
35

Data Source:
HPRD (in vitro, in vivo)

		MARCHF2	STX6
Description		membrane associated ring-CH-type finger 2	syntaxin 6
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Endocytosis Protein Ubiquitination	Intracellular Protein Transport Vesicle Fusion Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways			Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Creutzfeldt-Jakob disease (sporadic) ( 32949544) Intralaminar thalamic nuclei volume ( 34006833) Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		34 interacting genes: AQP6 CCL4 CD79A CDC34 CFTR CREB3L1 ECSIT ERGIC3 F11R FAM209A FATE1 FBXL12 GJA8 GPX8 IKBKG KASH5 LDLRAD1 LGR4 MUC1 PEX12 PLPPR2 SCN3B SSMEM1 STX6 SYNE4 TMEM106C TMEM179B TMEM52B TMEM86B TSPAN12 TSPO2 UBE2D1 UBE2E1 UBE2H	35 interacting genes: AQP6 ARMC8 DNAJC5 EBP EEA1 FAM210B GOLM2 GOPC LIME1 LMNA MARCHF2 MEOX2 MMGT1 MTERF2 MTIF3 NAPB PSMA3 PTPN9 SCN3B SNAP23 SNAP29 STOM STX16 STX1A STX2 STX4 STX7 TIMMDC1 TMEM14B TMEM205 TMEM86B TMEM9 VAMP4 VPS11 VPS18
Entrez ID		51257	10228
HPRD ID		14361	07231
Ensembl ID		ENSG00000099785	ENSG00000135823
Uniprot IDs		Q9P0N8	O43752
PDB IDs			2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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